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Anti-fn1 Antibody Fab (CAT#: MOM-18563-F(E))

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human fn1 Antibody Fab Fragment MOM-18563-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment is bind to Human FN1, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • FN1
  • Type
  • Fab
  • Immunogen
  • A region in the ED-A domain of human cellular fibronectin.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Purity
  • >95%, by SDS-PAGE with silver staining, under reducing conditions.
  • Storage
  • At -20°C for one year.

BACKGROUND

  • Antigen Description
  • Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
  • Function
  • collagen binding; extracellular matrix structural constituent; heparin binding; protein binding;
  • Synonyms
  • FN1; fibronectin 1; fibronectin; CIG; cold insoluble globulin; FINC; GFND2; LETS; migration stimulating factor; MSF; cold-insoluble globulin; migration-stimulating factor; FN; FNZ; ED-B; GFND; DKFZp686H0342; DKFZp686I1370; DKFZp686F10164; DKFZp686O13149;

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